I am right handed and grew up using spinning gear for righties. When I started using baitcasters about 5 years ago I immediately liked using left handed casting reels. It felt way more natural from the start and even now I don't like using friends' right handed casting reels. Like what everybody else has said, just use what's most comfortable. I don't know of advantages for either side except that you don't have to switch hands after casting when using a left handed reel, if you see that as an advantage.